Interactor 1: SPIKE (P59594)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S
Interactor 2: SPIKE (P59594)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S
Species: Severe acute respiratory syndrome-related coronavirus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.992 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16809285, 15043961, 15474492, 15518555, 16765058, 33845483, 33556147, 888800000220, 888800000810, 14996844, 15313178, 15345712, 16507566, 16873249, 16981695, 17957264, 18540634, 24519901, 28008928, 28393837 and 10 others
more... |
| Identification Methods | pull down, unspecified method, affinity chromatography technology, x-ray crystallography, protein complementation assay, biochemical, circular dichroism, comigration in sds page, electron microscopy, surface plasmon resonance and 4 others
more... |
| Interaction Type | direct interaction, physical association, association, covalent binding |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | bCoV_S1_N~bCoV_S1_N, bCoV_S1_N~bCoV_S1_RBD, CoV_S1_C~bCoV_S1_N, CoV_S2~bCoV_S1_N, bCoV_S1_RBD~bCoV_S1_RBD, CoV_S1_C~bCoV_S1_RBD, CoV_S2~bCoV_S1_RBD, CoV_S1_C~CoV_S2, CoV_S2~CoV_S2 |
| Common GO terms | GO:0016020 - membrane GO:0019031 - viral envelope GO:0019064 - fusion of virus membrane with host plasma membrane GO:0020002 - host cell plasma membrane GO:0039587 - suppression by virus of host tetherin activity and 8 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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| + | Sa |   |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
