Protein: BCL9
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)

Gene: BCL9
Organism: Homo sapiens
Interactions: 86
UniProt ID: O00512

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0005801 - cis-Golgi network
GO:0006366 - transcription by RNA polymerase II
GO:0008013 - beta-catenin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

138975

CTNB1
Catenin beta-1

5

20

Small-scale

0.926

High

139033

PYGO1
Pygopus homolog 1

4

17

Small-scale

0.705

High

139021

PYGO2
Pygopus homolog 2

4

4

Small-scale

0.691

High

139018

ISL2
Insulin gene enhancer protein ISL-2

2

20

High-throughput

0.611

High

138949

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

138978

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

138996

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

139017

LHX4
LIM/homeobox protein Lhx4

2

20

High-throughput

0.584

High

139008

CDC73
Parafibromin

2

2

Small-scale

0.571

High

139016

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

6

Small-scale

0.512

High

138950

TBXT
T-box transcription factor T

1

13

High-throughput

0.479

High

138951

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

138952

KLF4
Krueppel-like factor 4

1

20

High-throughput

0.479

High

138953

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

138954

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.479

High

138955

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

138957

FOS
Protein c-Fos

1

20

High-throughput

0.479

High

138958

IL1A
Interleukin-1 alpha

1

3

Small-scale

0.479

High

138959

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

138960

GELS
Gelsolin

1

1

High-throughput

0.479

High

138961

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

138962

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

138963

HSP7C
Heat shock cognate 71 kDa protein

1

5

Small-scale

0.479

High

138964

EGR2
E3 SUMO-protein ligase EGR2

1

11

High-throughput

0.479

High

138965

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.479

High

138966

MYOD1
Myoblast determination protein 1

1

9

High-throughput

0.479

High

138967

ITF2
Transcription factor 4

1

3

Small-scale

0.479

High

138968

GATA1
Erythroid transcription factor

1

15

High-throughput

0.479

High

138969

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

138970

GATA2
Endothelial transcription factor GATA-2

1

15

High-throughput

0.479

High

138971

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

15

High-throughput

0.479

High

138972

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

138976

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

138977

ETV4
ETS translocation variant 4

1

20

High-throughput

0.479

High

138979

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

138980

LHX1
LIM/homeobox protein Lhx1

1

20

High-throughput

0.479

High

138981

CEBPA
CCAAT/enhancer-binding protein alpha

1

20

High-throughput

0.479

High

138984

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

138985

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.479

High

138988

ISL1
Insulin gene enhancer protein ISL-1

1

20

High-throughput

0.479

High

138989

LMO4
LIM domain transcription factor LMO4

1

20

High-throughput

0.479

High

138990

SSBP2
Single-stranded DNA-binding protein 2

1

8

High-throughput

0.479

High

138991

EWS
RNA-binding protein EWS

1

13

High-throughput

0.479

High

138992

IRF8
Interferon regulatory factor 8

1

11

High-throughput

0.479

High

138993

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.479

High

138994

TLE3
Transducin-like enhancer protein 3

1

12

High-throughput

0.479

High

138995

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

138997

FOXI1
Forkhead box protein I1

1

14

High-throughput

0.479

High

138999

CUL3
Cullin-3

1

10

High-throughput

0.479

High

139000

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

139001

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

6

High-throughput

0.479

High

139002

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

139003

PLEC
Plectin

1

7

Small-scale

0.479

High

139004

DDB1
DNA damage-binding protein 1

1

4

Small-scale

0.479

High

139005

TBR1
T-box brain protein 1

1

13

High-throughput

0.479

High

139010

LDB1
LIM domain-binding protein 1

1

2

High-throughput

0.479

High

139011

BCL9L
B-cell CLL/lymphoma 9-like protein

1

11

High-throughput

0.479

High

139012

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

7

High-throughput

0.479

High

139013

NUP35
Nucleoporin NUP35

1

7

High-throughput

0.479

High

139014

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

139019

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

11

High-throughput

0.479

High

139022

SSBP4
Single-stranded DNA-binding protein 4

1

10

High-throughput

0.479

High

139023

SSBP3
Single-stranded DNA-binding protein 3

1

13

High-throughput

0.479

High

139026

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

139027

GCM1
Chorion-specific transcription factor GCMa

1

3

High-throughput

0.479

High

139029

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

139030

LHX3
LIM/homeobox protein Lhx3

1

20

High-throughput

0.479

High

139031

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

139034

ORC6
Origin recognition complex subunit 6

1

1

High-throughput

0.479

High

139025

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

3

High-throughput

0.457

High

138974

CTNA1
Catenin alpha-1

1

1

Small-scale

0.445

High

138956

EYA4
Protein phosphatase EYA4

1

19

High-throughput

0.437

High

138973

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.437

High

138982

LHX2
LIM/homeobox protein Lhx2

1

20

High-throughput

0.437

High

138983

KIF11
Kinesin-like protein KIF11

1

3

Small-scale

0.437

High

138986

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.437

High

138987

EPIPL
Epiplakin

1

7

Small-scale

0.437

High

138998

FOXL1
Forkhead box protein L1

1

14

High-throughput

0.437

High

139007

LHX8
LIM/homeobox protein Lhx8

1

20

High-throughput

0.437

High

139009

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

11

High-throughput

0.437

High

139015

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.437

High

139020

FEV
Protein FEV

1

20

High-throughput

0.437

High

139028

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

10

High-throughput

0.437

High

139032

LHX6
LIM/homeobox protein Lhx6

1

20

High-throughput

0.437

High

139006

KLH22
Kelch-like protein 22

1

3

High-throughput

0.407

High

139024

B2L13
Bcl-2-like protein 13

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025