Interactor 1: SPIKE (P59594)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S

Interactor 2: NS7A (P59635)
ORF7a protein (Accessory protein 7a) (Protein U122) (Protein X4)
Gene: 7a

Species: Severe acute respiratory syndrome-related coronavirus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.55 0.593

The method score is based on:

Property Details
Experiments 17520018, 16840309
Identification Methods two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0039587 - suppression by virus of host tetherin activity
GO:0044173 - host cell endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0055036 - virion membrane
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024