HitPredict

Interactor 1: KR122 (P59991)
Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2)
Gene: KRTAP12-2

Interactor 2: LCE4A (Q5TA78)
Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A)
Gene: LCE4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 146 Hs			1 99
+	Hs
		1135636 KRA93_HUMAN (5-140): 5.98e-27: 100: 25.95		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135640 KRA44_HUMAN (1-145): 1.7e-25: 96.6: 28.31		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135635 KRA94_HUMAN (5-140): 3.97e-25: 95.5: 27.27		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135645 KRA15_HUMAN (5-145): 1.09e-21: 87: 26.25		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		889788 KR109_HUMAN (5-130): 2.29e-20: 86.2: 29.37		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135631 KR412_HUMAN (6-141): 1.98e-20: 84.7: 25.63		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135634 KRA98_HUMAN (23-139): 1.13e-19: 81.6: 30.53		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135626 KRA13_HUMAN (4-145): 4.05e-19: 80.4: 22.60		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		889067 KR105_HUMAN (3-119): 9.74e-18: 78.9: 25.68		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135637 KRA92_HUMAN (23-145): 2e-17: 76.2: 24.24		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135641 KRA42_HUMAN (28-146): 7.21e-17: 73.5: 27.73		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135638 KR411_HUMAN (1-115): 1.49e-15: 71.6: 33.04		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		888557 KR123_HUMAN (1-96): 3.44e-16: 70.8: 50.00		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		889518 KR108_HUMAN (23-145): 8.65e-15: 70.8: 26.98		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		888654 KR124_HUMAN (1-99): 1.91e-14: 66.6: 37.14		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		991586 KRA11_HUMAN (59-145): 5.86e-13: 64.3: 35.96		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		889277 KR107_HUMAN (1-95): 3.28e-11: 61.6: 34.69		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		889162 KR106_HUMAN (4-146): 2.88e-09: 55.8: 27.27		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		1135639 KRA45_HUMAN (8-135): 1.64e-09: 55.4: 31.25		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00
+	Hs
		888710 KR101_HUMAN (1-89): 5.61e-09: 54.6: 30.34		LCE4A_HUMAN (1-99): 6.8e-40: 129: 100.00