HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: CORO (Q06440)
Coronin-like protein
Gene: CRN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	25362487, 11805837, 9885246, 21454476
Identification Methods	cosedimentation in solution, cross-linking study, anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 375 Sc			1 651
+	Hs
		892108 ACTB_HUMAN (1-375): 0: 601: 88.80		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		930051 ACTG_HUMAN (1-375): 0: 600: 89.07		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932449 ACTC_HUMAN (2-375): 0: 591: 87.17		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932355 ACTC_HUMAN (2-375): 0: 591: 87.17		COR1B_HUMAN (1-487): 4.21e-88: 285: 34.89
+	Hs
		891943 ACTB_HUMAN (1-375): 0: 601: 88.80		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		929956 ACTG_HUMAN (1-375): 0: 600: 89.07		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		884627 ACTB_HUMAN (1-375): 0: 601: 88.80		CORO7_HUMAN (7-431): 1.7e-67: 239: 26.62
+	Hs
		903280 ACTBL_HUMAN (2-375): 0: 687: 83.42		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		891660 ACTB_HUMAN (1-375): 0: 601: 88.80		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		903110 ACTG_HUMAN (1-375): 0: 600: 89.07		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		932318 ACTC_HUMAN (2-375): 0: 591: 87.17		SNR40_HUMAN (314-524): 2.37e-09: 61.7: 11.27