HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: SCP1 (Q08873)
Transgelin (Calponin homolog 1)
Gene: SCP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.879

Property	Details
Experiments	12857851, 12868959, 18400761
Identification Methods	biochemical, cosedimentation in solution, light scattering, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 375 Sc			1 200
+	Hs
		891782 ACTB_HUMAN (1-375): 0: 601: 88.80		CNN3_HUMAN (1-199): 9.26e-73: 224: 25.13
+	Hs
		932175 ACTC_HUMAN (2-375): 0: 591: 87.17		CNN3_HUMAN (1-199): 9.26e-73: 224: 25.13
+	Hs
		891988 ACTB_HUMAN (1-375): 0: 601: 88.80		CNN2_HUMAN (2-199): 9.06e-69: 213: 25.25
+	Hs
		741850 ACTB_HUMAN (1-375): 0: 601: 88.80		TAGL2_HUMAN (5-200): 1.44e-66: 204: 30.50
+	Hs
		741855 ACTG_HUMAN (1-375): 0: 600: 89.07		TAGL2_HUMAN (5-200): 1.44e-66: 204: 30.50
+	Hs
		932344 ACTC_HUMAN (2-375): 0: 591: 87.17		CNN2_HUMAN (2-199): 9.06e-69: 213: 25.25
+	Rn
		933100 ACTS_RAT (2-375): 0: 590: 86.90		CNN1_RAT (2-199): 5.18e-67: 209: 23.74
+	Hs
		851163 ACTS_HUMAN (2-375): 0: 590: 86.90		CNN1_HUMAN (2-199): 2.5e-66: 207: 24.24
+	Hs
		741856 ACTC_HUMAN (2-375): 0: 591: 87.17		TAGL2_HUMAN (5-200): 1.44e-66: 204: 30.50
+	Hs
		891748 ACTB_HUMAN (1-375): 0: 601: 88.80		IQGA2_HUMAN (4-181): 2.36e-48: 170: 19.02
+	Hs
		809232 ACTB_HUMAN (1-375): 0: 601: 88.80		IQGA1_HUMAN (4-181): 5.08e-48: 169: 17.39
+	Hs
		809257 ACTG_HUMAN (1-375): 0: 600: 89.07		IQGA1_HUMAN (4-181): 5.08e-48: 169: 17.39
+	Dm
		862565 ACT3_DROME (2-375): 0: 593: 87.97		Q9I7J0_DROME (22-199): 5.64e-56: 176: 32.02
+	Sp
		144980 ACT_SCHPO (1-375): 0: 591: 89.60		IQG1_SCHPO (6-144): 3.1e-36: 135: 20.86
+	Hs
		892114 ACTB_HUMAN (1-375): 0: 601: 88.80		LIMC1_HUMAN (31-165): 6.2e-32: 123: 18.37
+	Hs
		933037 ACTS_HUMAN (2-375): 0: 590: 86.90		LRCH3_HUMAN (17-140): 3.52e-34: 129: 24.80
+	Sc
		887718 ACT_YEAST (1-375): 0: 594: 100.00		IQG1_YEAST (4-149): 2.67e-32: 124: 24.00
+	Hs
		891926 ACTB_HUMAN (1-375): 0: 601: 88.80		LMO7_HUMAN (36-153): 9.72e-14: 71: 23.85
+	Hs
		932285 ACTC_HUMAN (2-375): 0: 591: 87.17		LMO7_HUMAN (36-153): 9.72e-14: 71: 23.85