HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 4684
+	Hs
		756209 MCM7_HUMAN (188-886): 0: 707: 27.35		PLEC_HUMAN (1-4684): 0: 1793: 100.00
+	Hs
		555636 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		887880 MCM2_HUMAN (1-904): 0: 1078: 100.00		EPIPL_HUMAN (4390-4637): 2.39e-28: 129: 29.25
+	Hs
		888393 MCM2_HUMAN (1-904): 0: 1078: 100.00		MACF1_HUMAN (4268-4616): 1.6e-15: 87: 19.48
+	Hs
		555616 MCM5_HUMAN (169-902): 0: 768: 29.43		ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90
+	Hs
		887991 MCM2_HUMAN (1-904): 0: 1078: 100.00		DYST_HUMAN (3439-3682): 1.46e-13: 80.3: 20.90
+	Hs
		587591 MCM2_HUMAN (1-904): 0: 1078: 100.00		DESP_HUMAN (404-1000): 1.7e-12: 76.9: 9.56
+	Hs
		587572 MCM5_HUMAN (169-902): 0: 768: 29.43		DESP_HUMAN (404-1000): 1.7e-12: 76.9: 9.56