HitPredict

Interactor 1: RPO10 (P60292)
DNA-directed RNA polymerase subunit Rpo10 (EC 2.7.7.6) (DNA-directed RNA polymerase subunit N)
Gene: RPO10

Interactor 2: Q8U0M3 (Q8U0M3)
DNA-directed RNA polymerase subunit beta (EC 2.7.7.6)
Gene: PF1564

Species: Pyrococcus furiosus DSM 3638

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21386817
Identification Methods	molecular sieving
Interaction Type	association

Property	Details
Interacting Pfam domains	RNA_pol_N~RNA_pol_Rpb2_6
Common GO terms	GO:0000428 - DNA-directed RNA polymerase complex GO:0001055 - RNA polymerase II activity GO:0003677 - DNA binding GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 65 Pf			1 1117
+	Hs
		676857 RPAB5_HUMAN (1-62): 3.47e-31: 104: 53.23		RPB2_HUMAN (8-1112): 0: 1456: 40.10
+	Hs
		921179 RPAB5_HUMAN (1-62): 3.47e-31: 104: 53.23		RPC2_HUMAN (9-1115): 0: 1383: 37.50
+	Sp
		143460 RPAB5_SCHPO (1-62): 4.78e-30: 101: 51.61		RPB2_SCHPO (9-1115): 0: 1369: 39.00
+	Sc
		439971 RPAB5_YEAST (1-62): 5.12e-27: 94.2: 53.97		RPB2_YEAST (9-1111): 0: 1365: 39.25
+	Sc
		604649 RPAB5_YEAST (1-62): 5.12e-27: 94.2: 53.97		RPC2_YEAST (2-1115): 0: 1336: 38.17
+	Hs
		921169 RPAB5_HUMAN (1-62): 3.47e-31: 104: 53.23		RPA2_HUMAN (3-1113): 0: 1177: 29.81
+	Sc
		604498 RPAB5_YEAST (1-62): 5.12e-27: 94.2: 53.97		RPA2_YEAST (19-1116): 0: 1024: 26.53
+	Hv
		89544 D4GWX5_HALVD (1-63): 6.58e-26: 91.1: 56.25		D4GZX5_HALVD (518-1117): 0: 778: 58.57
+	Hv
		89543 D4GWX5_HALVD (1-63): 6.58e-26: 91.1: 56.25		D4GZX4_HALVD (17-508): 8.27e-161: 488: 49.80