Protein: DDX11
ATP-dependent DNA helicase DDX11 (EC 5.6.2.3) (CHL1-related protein 1) (hCHLR1) (DEAD/H-box protein 11) (DNA 5'-3' helicase DDX11) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2)

Gene: DDX11
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q96FC9

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000922 - spindle pole
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1390475

FUZZY
Protein fuzzy homolog

3

1

High-throughput

0.656

High

277463

AVIL
Advillin

2

2

High-throughput

0.628

High

1316762

WDFY3
WD repeat and FYVE domain-containing protein 3

2

2

High-throughput

0.628

High

1390481

DOCK5
Dedicator of cytokinesis protein 5

2

1

High-throughput

0.628

High

888478

TSP3
Thrombospondin-3

3

2

High-throughput

0.609

High

1042659

UPAR
Urokinase plasminogen activator surface receptor

3

1

High-throughput

0.609

High

946514

YBEY
Endoribonuclease YbeY

2

0

High-throughput

0.602

High

1101875

SKP2
S-phase kinase-associated protein 2

2

0

High-throughput

0.602

High

1382613

AZIN2
Antizyme inhibitor 2

2

0

High-throughput

0.602

High

1390468

TET5A
Terminal nucleotidyltransferase 5A

2

0

High-throughput

0.602

High

1390484

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

0

High-throughput

0.602

High

259040

DNJA2
DnaJ homolog subfamily A member 2

2

3

High-throughput

0.601

High

551198

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.559

High

1390478

CAD19
Cadherin-19

2

2

High-throughput

0.558

High

317742

NOL4
Nucleolar protein 4

1

1

High-throughput

0.536

High

549657

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

2

High-throughput

0.536

High

933209

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

1

High-throughput

0.536

High

1022933

EFNB1
Ephrin-B1

1

2

High-throughput

0.536

High

1258261

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

1

High-throughput

0.536

High

1390473

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.536

High

1390479

CAD23
Cadherin-23

1

1

High-throughput

0.536

High

332033

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.518

High

762480

PROF2
Profilin-2

1

0

High-throughput

0.518

High

443918

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

2

High-throughput

0.515

High

642577

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.513

High

651700

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

High-throughput

0.513

High

1152380

ZN174
Zinc finger protein 174

1

0

High-throughput

0.513

High

1218059

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.513

High

1390469

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

1390474

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1390486

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.513

High

190458

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.489

High

1390336

I17RA
Interleukin-17 receptor A

1

2

High-throughput

0.489

High

294166

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

414396

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

814559

FEN1
Flap endonuclease 1

1

3

Small-scale

0.479

High

984237

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

1106036

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.479

High

1113976

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1357877

CTF18
Chromosome transmission fidelity protein 18 homolog

1

1

Small-scale

0.479

High

1390472

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1390480

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1390491

TIM
Protein timeless homolog

1

1

Small-scale

0.479

High

1390482

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

187546

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.458

High

769889

RFC2
Replication factor C subunit 2

1

0

Small-scale

0.458

High

860582

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

1390476

DCC1
Sister chromatid cohesion protein DCC1

1

0

Small-scale

0.458

High

97009

E9PK12
Fuzzy planar cell polarity protein

1

1

High-throughput

0.445

High

239168

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.445

High

844852

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.445

High

1390471

Q96KY9
CDH19 protein

1

2

High-throughput

0.407

High

1390487

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

3

High-throughput

0.407

High

1381157

SNX21
Sorting nexin-21

2

0

High-throughput

0.328

High

1390483

TOM22
Mitochondrial import receptor subunit TOM22 homolog

2

0

High-throughput

0.328

High

1390485

KBTB4
Kelch repeat and BTB domain-containing protein 4

2

0

High-throughput

0.328

High

1390488

GGT7
Glutathione hydrolase 7

2

0

High-throughput

0.328

High

1390490

PCDA4
Protocadherin alpha-4

2

0

High-throughput

0.328

High

570709

EDN3
Endothelin-3

1

0

High-throughput

0.279

Low

1323919

KLH34
Kelch-like protein 34

1

0

High-throughput

0.279

Low

1387694

ERP27
Endoplasmic reticulum resident protein 27

1

0

High-throughput

0.279

Low

1390470

HIPL1
HHIP-like protein 1

1

0

High-throughput

0.279

Low

1390477

SMG9
Nonsense-mediated mRNA decay factor SMG9

1

0

High-throughput

0.279

Low

1390489

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

1091895

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.269

Low

1206515

PRC2B
Protein PRRC2B

1

0

High-throughput

0.251

Low

1383644

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025