Protein: TSP3
Thrombospondin-3

Gene: TSP3, THBS3
Organism: Homo sapiens
Interactions: 78
UniProt ID: P49746

Gene Ontology (top 5):
GO:0003417 - growth plate cartilage development
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0007160 - cell-matrix adhesion
GO:0008201 - heparin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

464428

TSP1
Thrombospondin-1

3

17

High-throughput

0.861

High

771550

TSP4
Thrombospondin-4

3

20

High-throughput

0.861

High

888447

TBA4A
Tubulin alpha-4A chain

3

3

High-throughput

0.667

High

888441

TSP3
Thrombospondin-3

1

17

Small-scale

0.647

High

127021

APBB1
Amyloid beta precursor protein binding family B member 1

3

1

High-throughput

0.609

High

542388

TOP2A
DNA topoisomerase 2-alpha

3

1

High-throughput

0.609

High

888445

CORO7
Coronin-7

3

2

High-throughput

0.609

High

888446

RL23
Large ribosomal subunit protein uL14

3

2

High-throughput

0.609

High

888449

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

3

1

High-throughput

0.609

High

888452

TROP
Trophinin

3

2

High-throughput

0.609

High

888454

PEX6
Peroxisomal ATPase PEX6

3

2

High-throughput

0.609

High

888458

TBB8
Tubulin beta-8 chain

3

1

High-throughput

0.609

High

888468

ASCC3
Activating signal cointegrator 1 complex subunit 3

3

2

High-throughput

0.609

High

888474

ARHG1
Rho guanine nucleotide exchange factor 1

3

3

High-throughput

0.609

High

888478

DDX11
ATP-dependent DNA helicase DDX11

3

2

High-throughput

0.609

High

888487

MCM9
DNA helicase MCM9

3

3

High-throughput

0.609

High

532452

CH60
60 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.558

High

769949

RFC1
Replication factor C subunit 1

2

3

High-throughput

0.558

High

888453

TBB3
Tubulin beta-3 chain

2

1

High-throughput

0.558

High

888465

TBA1A
Tubulin alpha-1A chain

2

3

High-throughput

0.558

High

888448

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.536

High

888482

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

2

7

High-throughput

0.533

High

697807

CALR
Calreticulin

1

7

High-throughput

0.515

High

213862

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

5

High-throughput

0.489

High

552168

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

888477

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.489

High

725592

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

2

High-throughput

0.479

High

888457

PKN2
Serine/threonine-protein kinase N2

1

4

High-throughput

0.479

High

787937

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.470

High

888472

NEK7
Serine/threonine-protein kinase Nek7

1

8

High-throughput

0.470

High

219069

RA51C
DNA repair protein RAD51 homolog 3

1

0

High-throughput

0.458

High

888492

DYN3
Dynamin-3

1

0

High-throughput

0.458

High

387956

FIBG
Fibrinogen gamma chain

1

8

High-throughput

0.445

High

135902

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.437

High

217962

TGON2
Trans-Golgi network integral membrane protein 2

1

17

High-throughput

0.437

High

231685

PEX1
Peroxisomal ATPase PEX1

1

2

High-throughput

0.437

High

425788

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

1

High-throughput

0.437

High

539783

RALA
Ras-related protein Ral-A

1

15

High-throughput

0.437

High

547112

PYC
Pyruvate carboxylase, mitochondrial

1

1

High-throughput

0.437

High

888442

PPOX
Protoporphyrinogen oxidase

1

2

High-throughput

0.437

High

888476

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

1

High-throughput

0.437

High

888480

TCPH
T-complex protein 1 subunit eta

1

2

High-throughput

0.437

High

888488

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.437

High

888491

TBD2B
TBC1 domain family member 2B

1

2

High-throughput

0.437

High

888444

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.407

High

238443

RAD21
Double-strand-break repair protein rad21 homolog

3

0

High-throughput

0.347

High

649874

ADRO
NADPH:adrenodoxin oxidoreductase, mitochondrial

3

0

High-throughput

0.347

High

888443

BIEA
Biliverdin reductase A

3

0

High-throughput

0.347

High

888455

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

3

0

High-throughput

0.347

High

888456

DIP2A
Disco-interacting protein 2 homolog A

3

0

High-throughput

0.347

High

888459

TIGD5
Tigger transposable element-derived protein 5

3

0

High-throughput

0.347

High

888460

IQEC2
IQ motif and SEC7 domain-containing protein 2

3

0

High-throughput

0.347

High

888470

FANCB
Fanconi anemia group B protein

3

0

High-throughput

0.347

High

888471

SMG8
Nonsense-mediated mRNA decay factor SMG8

3

0

High-throughput

0.347

High

888479

CE034
Uncharacterized protein C5orf34

3

0

High-throughput

0.347

High

888485

PAPD1
Poly(A) RNA polymerase, mitochondrial

3

0

High-throughput

0.347

High

888486

MKS1
Tectonic-like complex member MKS1

3

0

High-throughput

0.347

High

888489

SH3B4
SH3 domain-binding protein 4

3

0

High-throughput

0.347

High

888493

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

3

0

High-throughput

0.347

High

888473

HASP
Serine/threonine-protein kinase haspin

2

0

High-throughput

0.328

High

229127

GTPB6
Putative GTP-binding protein 6

2

0

High-throughput

0.318

High

888462

C19L1
CWF19-like protein 1

2

0

High-throughput

0.318

High

888467

TRM44
Probable tRNA

2

0

High-throughput

0.318

High

888464

BORA
Protein aurora borealis

1

0

High-throughput

0.279

Low

168830

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

328233

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.249

Low

888450

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

888451

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.249

Low

888461

INT11
Integrator complex subunit 11

1

0

High-throughput

0.249

Low

888463

TTLL5
Tubulin polyglutamylase TTLL5

1

0

High-throughput

0.249

Low

888466

BBS7
BBSome complex member BBS7

1

0

High-throughput

0.249

Low

888469

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.249

Low

888475

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.249

Low

888481

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.249

Low

888483

NOL11
Nucleolar protein 11

1

0

High-throughput

0.249

Low

888484

RIC8B
Chaperone Ric-8B

1

0

High-throughput

0.249

Low

888490

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025