Protein: RYR2
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)

Gene: RYR2
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q92736

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0002027 - regulation of heart rate
GO:0003143 - embryonic heart tube morphogenesis
GO:0003220 - left ventricular cardiac muscle tissue morphogenesis
GO:0003300 - cardiac muscle hypertrophy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932950

FKB1B
Peptidyl-prolyl cis-trans isomerase FKBP1B

4

10

Small-scale

0.900

High

1270172

RYR2
Ryanodine receptor 2

3

16

Small-scale

0.861

High

601672

RYR1
Ryanodine receptor 1

2

17

Small-scale

0.799

High

675323

SORCN
Sorcin

2

7

Small-scale

0.768

High

568750

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

12

Small-scale

0.724

High

183386

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

2

Small-scale

0.647

High

609684

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

12

Small-scale

0.647

High

610755

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

12

Small-scale

0.647

High

966318

CAC1D
Voltage-dependent L-type calcium channel subunit alpha-1D

1

10

Small-scale

0.647

High

1047189

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

Small-scale

0.647

High

923834

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

10

Small-scale

0.618

High

1039134

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

11

Small-scale

0.618

High

1073364

RYR3
Ryanodine receptor 3

1

16

Small-scale

0.618

High

962895

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

High-throughput

0.578

High

135945

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

10

Small-scale

0.561

High

363865

ALBU
Albumin

1

2

High-throughput

0.536

High

529501

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

1033845

SNTA1
Alpha-1-syntrophin

1

2

Small-scale

0.536

High

1270174

SMAD5
Mothers against decapentaplegic homolog 5

1

6

High-throughput

0.508

High

834322

PSN1
Presenilin-1

1

1

Small-scale

0.501

High

1022794

AKAP6
A-kinase anchor protein 6

1

12

Small-scale

0.501

High

1205715

HOME1
Homer protein homolog 1

1

10

Small-scale

0.501

High

1263749

JPH3
Junctophilin-3

1

4

Small-scale

0.501

High

1270173

JPH4
Junctophilin-4

1

4

Small-scale

0.501

High

377551

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

582414

NUCL
Nucleolin

1

4

High-throughput

0.479

High

734718

TRI23
E3 ubiquitin-protein ligase TRIM23

1

5

High-throughput

0.479

High

1074956

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

995099

GOGA2
Golgin subfamily A member 2

1

13

High-throughput

0.470

High

1080882

HSPB2
Heat shock protein beta-2

1

1

High-throughput

0.464

High

578350

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

1270175

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

19

High-throughput

0.457

High

131267

BIN1
Myc box-dependent-interacting protein 1

1

3

High-throughput

0.457

High

734479

ARL2
ADP-ribosylation factor-like protein 2

1

3

High-throughput

0.437

High

869698

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.437

High

1146688

A16L1
Autophagy-related protein 16-1

1

15

High-throughput

0.437

High

1244408

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.437

High

1270176

SAR1A
Small COPII coat GTPase SAR1A

1

8

High-throughput

0.437

High

1270177

SAR1B
Small COPII coat GTPase SAR1B

1

5

High-throughput

0.437

High


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Last updated: 15 Jul 2024