HitPredict

Interactor 1: D4A332 (D4A332)
Ankyrin repeat and LEM domain containing 1
Gene: Ankle1

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~fn3, Ank_2~Recep_L_domain
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 518 Rn			1 1383
+	Hs
		872428 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		EPHA5_HUMAN (662-1320): 0: 581: 24.11
+	Hs
		665584 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		EPHB2_HUMAN (662-1317): 0: 577: 23.01
+	Hs
		872634 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		EPHA4_HUMAN (662-1328): 0: 570: 24.19
+	Hs
		980379 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		EPHA7_HUMAN (664-1321): 0: 568: 22.55
+	Hs
		872504 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		EPHA5_HUMAN (662-1320): 0: 581: 24.11
+	Hs
		665439 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		EPHA3_HUMAN (661-1320): 4.01e-172: 541: 24.15
+	Hs
		665360 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		666579 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		980386 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72
+	Hs
		980385 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		385170 ANR44_HUMAN (2-390): 1.4e-50: 188: 12.90		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		1083907 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72
+	Hs
		385704 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Rn
		728451 KDIS_RAT (1-183): 3.79e-43: 166: 17.20		NTRK1_RAT (997-1287): 8.91e-65: 238: 41.28
+	Hs
		1081644 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80
+	Hs
		166874 ANR28_HUMAN (1-201): 1.54e-38: 152: 14.71		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		338310 NOTC2_HUMAN (2-391): 2.11e-66: 235: 18.82		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		602024 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		339124 KDIS_HUMAN (1-183): 3.09e-43: 166: 16.67		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		338353 ANK3_HUMAN (1-128): 2.86e-34: 140: 24.22		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50