HitPredict

Interactor 1: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000146 - microfilament motor activity GO:0005829 - cytosol GO:0016020 - membrane GO:0016459 - myosin complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 151 Hs			1 2157
+	Hs
		538665 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		483925 CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		483999 CALM2_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		484117 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Dm
		870146 MLC2_DROME (1-151): 6.78e-55: 171: 53.64		MYO7A_DROME (87-1086): 0: 893: 26.95
+	Hs
		484218 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO5B_HUMAN (67-1775): 0: 948: 19.62
+	Dm
		906697 CALM_DROME (5-77): 1.5e-11: 60.2: 28.77		MYO7A_DROME (87-1086): 0: 893: 26.95
+	Hs
		70646 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		728458 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		MYH11_HUMAN (797-1250): 8.31e-81: 299: 20.46
+	Hs
		484206 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO5C_HUMAN (736-1249): 8.8e-96: 347: 19.74
+	Hs
		441665 MYL3_HUMAN (3-150): 2.39e-55: 173: 73.33		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02
+	Hs
		538642 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02
+	Hs
		484202 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO10_HUMAN (792-1023): 2.21e-34: 147: 35.44
+	Hs
		724737 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02
+	Hs
		648611 CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03		MYO10_HUMAN (792-1023): 2.21e-34: 147: 35.44
+	Sp
		251969 CALM_SCHPO (5-77): 4.59e-11: 59: 26.03		MYO51_SCHPO (823-1054): 8.01e-26: 119: 27.31
+	Sp
		293469 CALM_SCHPO (5-77): 4.59e-11: 59: 26.03		MYO52_SCHPO (818-1053): 1.68e-25: 118: 30.29
+	Hs
		648467 CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02