HitPredict

Interactor 1: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Interactor 2: MYO19 (Q96H55)
Unconventional myosin-XIX (Myosin head domain-containing protein 1)
Gene: MYO19

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000146 - microfilament motor activity GO:0005829 - cytosol GO:0016020 - membrane GO:0016459 - myosin complex GO:0031982 - vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 151 Hs			1 970
+	Hs
		538692 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYO19_HUMAN (1-970): 0: 1069: 100.00
+	Hs
		409452 MYL1_HUMAN (3-150): 1.84e-56: 176: 74.32		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		441666 MYL3_HUMAN (3-150): 2.39e-55: 173: 73.33		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		441665 MYL3_HUMAN (3-150): 2.39e-55: 173: 73.33		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Dm
		870146 MLC2_DROME (1-151): 6.78e-55: 171: 53.64		MYO7A_DROME (9-950): 0: 990: 27.25
+	Gg
		361265 MYL6_CHICK (1-151): 1.02e-51: 162: 89.40		MYH11_CHICK (9-907): 0: 993: 27.80
+	Hs
		538643 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		538642 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		728458 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		MYH11_HUMAN (2-965): 0: 1001: 26.34
+	Hs
		725124 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		MYH10_HUMAN (2-965): 0: 998: 26.14
+	Hs
		724737 MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00		MYH9_HUMAN (9-907): 0: 997: 28.63
+	Hs
		484218 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO5B_HUMAN (21-964): 0: 1002: 28.72
+	Hs
		484202 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO10_HUMAN (1-945): 0: 991: 26.68
+	Dm
		906697 CALM_DROME (5-77): 1.5e-11: 60.2: 28.77		MYO7A_DROME (9-950): 0: 990: 27.25
+	Hs
		538709 MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Sp
		251969 CALM_SCHPO (5-77): 4.59e-11: 59: 26.03		MYO51_SCHPO (39-820): 1.83e-139: 454: 35.80
+	Hs
		483966 CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		484047 CALM2_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Hs
		484219 CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77		MYO6_HUMAN (50-677): 1.69e-119: 397: 36.01
+	Ss
		94703 F2Z5G3_PIG (5-77): 1.13e-11: 60.6: 28.77		MYO6_PIG (50-677): 1.83e-118: 394: 35.99