HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0030027 - lamellipodium
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1250
+	Hs
		932222 ACTC_HUMAN (2-375): 0: 592: 94.12		RAPH1_HUMAN (1-1250): 0: 627: 100.00
+	Hs
		915423 ACTA_HUMAN (2-375): 0: 591: 94.12		AB1IP_HUMAN (152-749): 2.63e-146: 459: 40.43
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 735: 91.71		MUC1_HUMAN (540-1249): 7.9e-36: 150: 11.97
+	Hs
		1122431 ACTBL_HUMAN (2-375): 0: 735: 91.71		SRCAP_HUMAN (502-1060): 1.36e-11: 71.8: 11.70
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 591: 94.12		MUC1_HUMAN (540-1249): 7.9e-36: 150: 11.97
+	Hs
		891853 ACTB_HUMAN (1-375): 0: 603: 100.00		SRCAP_HUMAN (502-1060): 1.36e-11: 71.8: 11.70
+	Hs
		929905 ACTG_HUMAN (1-375): 0: 601: 98.93		SRCAP_HUMAN (502-1060): 1.36e-11: 71.8: 11.70
+	Hs
		932156 ACTC_HUMAN (2-375): 0: 592: 94.12		MDC1_HUMAN (718-1249): 2.96e-14: 80.3: 14.37
+	Hs
		932219 ACTC_HUMAN (2-375): 0: 592: 94.12		SRCAP_HUMAN (502-1060): 1.36e-11: 71.8: 11.70
+	Dm
		501503 ACT1_DROME (2-375): 0: 598: 98.13		Q86BH2_DROME (642-1214): 2.13e-09: 64.5: 11.17