HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	11580269, 35271311
Identification Methods	x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Hs			1 535
+	Hs
		1122486 ACTBL_HUMAN (2-375): 0: 735: 91.71		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		943268 ACTBL_HUMAN (2-375): 0: 735: 91.71		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826692 ACTBL_HUMAN (2-375): 0: 735: 91.71		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		821244 ACTBL_HUMAN (2-375): 0: 735: 91.71		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		891991 ACTB_HUMAN (1-375): 0: 603: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		929984 ACTG_HUMAN (1-375): 0: 601: 98.93		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		929820 ACTG_HUMAN (1-375): 0: 601: 98.93		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		932351 ACTC_HUMAN (2-375): 0: 592: 94.12		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		932100 ACTC_HUMAN (2-375): 0: 592: 94.12		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		932952 ACTS_HUMAN (2-375): 0: 592: 93.58		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826593 ACTB_HUMAN (1-375): 0: 603: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826609 ACTG_HUMAN (1-375): 0: 601: 98.93		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826611 ACTC_HUMAN (2-375): 0: 592: 94.12		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		573194 ACTB_HUMAN (1-375): 0: 603: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821144 ACTB_HUMAN (1-375): 0: 603: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573210 ACTG_HUMAN (1-375): 0: 601: 98.93		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821160 ACTG_HUMAN (1-375): 0: 601: 98.93		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573212 ACTC_HUMAN (2-375): 0: 592: 94.12		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821162 ACTC_HUMAN (2-375): 0: 592: 94.12		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		821163 ACTS_HUMAN (2-375): 0: 592: 93.58		TCPE_HUMAN (1-528): 0: 541: 32.29