HitPredict

Interactor 1: ACTB (P60710)
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: FLNB (Q80X90)
Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)
Gene: FLNB

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31189591
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0001725 - stress fiber GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005903 - brush border and 1 others more... GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Mm			1 2602
+	Hs
		261242 ACTC_HUMAN (2-375): 0: 592: 94.12		FLNB_HUMAN (1-2602): 0: 2446: 95.85
+	Hs
		598031 ACTB_HUMAN (1-375): 0: 603: 100.00		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Hs
		598053 ACTG_HUMAN (1-375): 0: 601: 98.93		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Hs
		598055 ACTC_HUMAN (2-375): 0: 592: 94.12		FLNA_HUMAN (1-2602): 0: 2272: 68.98
+	Hs
		891763 ACTB_HUMAN (1-375): 0: 603: 100.00		FLNC_HUMAN (7-2602): 0: 1230: 34.74
+	Hs
		363200 ACTBL_HUMAN (2-375): 0: 735: 91.71		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		891697 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB2_HUMAN (6-370): 7.46e-104: 376: 27.85
+	Hs
		164588 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTN2_HUMAN (6-371): 8.97e-104: 375: 27.51
+	Hs
		929824 ACTG_HUMAN (1-375): 0: 601: 98.93		SPTB2_HUMAN (6-370): 7.46e-104: 376: 27.85
+	Hs
		506816 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB1_HUMAN (6-358): 1.46e-102: 371: 26.85
+	Hs
		932107 ACTC_HUMAN (2-375): 0: 592: 94.12		SPTB2_HUMAN (6-370): 7.46e-104: 376: 27.85
+	Hs
		211548 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN4_HUMAN (12-241): 1.63e-104: 361: 35.90
+	Hs
		211560 ACTC_HUMAN (2-375): 0: 592: 94.12		ACTN4_HUMAN (12-241): 1.63e-104: 361: 35.90
+	Hs
		211561 ACTS_HUMAN (2-375): 0: 592: 93.58		ACTN4_HUMAN (12-241): 1.63e-104: 361: 35.90
+	Hs
		513848 ACTS_HUMAN (2-375): 0: 592: 93.58		DMD_HUMAN (13-392): 2.33e-95: 349: 22.79
+	Hs
		725637 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN2_HUMAN (5-241): 5.87e-95: 332: 36.52
+	Oc
		933099 ACTS_RABIT (2-375): 0: 592: 93.58		Q07931_RABIT (5-267): 9.27e-104: 336: 34.08
+	Hs
		362988 ACTB_HUMAN (1-375): 0: 603: 100.00		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Hs
		363051 ACTG_HUMAN (1-375): 0: 601: 98.93		FINC_HUMAN (1321-2601): 3.77e-77: 288: 11.99
+	Dm
		284844 ACT1_DROME (2-375): 0: 598: 98.13		O77291_DROME (17-254): 4.55e-34: 147: 36.52