HitPredict

Interactor 1: ACTB (P60711)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: ESPN (Q63618)
Espin (Ectoplasmic specialization protein)
Gene: ESPN

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	12598619
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005737 - cytoplasm GO:0005903 - brush border GO:0015629 - actin cytoskeleton
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 375 Rn			1 837
+	Hs
		862022 ACTC_HUMAN (2-375): 0: 592: 94.12		DAPK1_HUMAN (2-267): 1.86e-70: 255: 26.69
+	Hs
		965115 ACTBL_HUMAN (2-375): 0: 735: 91.71		ANK2_HUMAN (1-89): 2.35e-17: 89.7: 23.60
+	Hs
		891882 ACTB_HUMAN (1-375): 0: 603: 100.00		ANKH1_HUMAN (1-194): 1.89e-38: 157: 27.55
+	Mm
		57374 ACTB_MOUSE (1-375): 0: 603: 100.00		A2AM57_MOUSE (174-438): 4.61e-29: 127: 15.69
+	Mm
		57380 ACTG_MOUSE (1-375): 0: 601: 98.93		A2AM57_MOUSE (174-438): 4.61e-29: 127: 15.69
+	Hs
		891699 ACTB_HUMAN (1-375): 0: 603: 100.00		ANK2_HUMAN (1-89): 2.35e-17: 89.7: 23.60
+	Rn
		251023 ACTB_RAT (1-375): 0: 603: 100.00		ANK3_RAT (1-89): 1.15e-16: 87.3: 22.47
+	Hs
		930079 ACTH_HUMAN (2-375): 0: 589: 93.58		ANK2_HUMAN (1-89): 2.35e-17: 89.7: 23.60