HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0031941 - filamentous actin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1068
+	Hs
		925335 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		545423 RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		1129136 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		951055 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		894102 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		900556 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		436347 RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		925433 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		725138 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		725125 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		1232332 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		892482 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		951148 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		894206 CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		900682 RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32		MILK1_HUMAN (963-1066): 1.29e-35: 148: 40.00
+	Hs
		724757 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		724776 RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		925387 RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71		MICA3_HUMAN (956-1067): 2.33e-14: 80.5: 38.05
+	Hs
		1186089 RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32		MICA3_HUMAN (956-1067): 2.33e-14: 80.5: 38.05
+	Hs
		892450 RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00		MICA3_HUMAN (956-1067): 2.33e-14: 80.5: 38.05