Interactor 1: GUAA (P49915)
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)
Gene: GMPS

Interactor 2: GUAA (P49915)
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)
Gene: GMPS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GATase~GATase, GATase~GMP_synt_C, GATase~NAD_synthase, GMP_synt_C~GMP_synt_C, GMP_synt_C~NAD_synthase, NAD_synthase~NAD_synthase
Common GO terms GO:0003921 - GMP synthase activity
GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006177 - GMP biosynthetic process
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 693
Hs

1 693
+ Hs
+ Pf
+ Mm
+ Sc
+ Ec
+ Ec
+ Ec

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Last updated: 11Aug2025