HitPredict

Interactor 1: IF4A1 (P60842)
Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1)
Gene: EIF4A1

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 28514442, 17353931, 29395067, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 406
Hs

1 1382
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024