Interactor 1: MMP14 (P50281)
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)
Gene: MMP14

Interactor 2: MMP15 (P51511)
Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2)
Gene: MMP15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Hemopexin~Hemopexin, Hemopexin~Peptidase_M10, Hemopexin~PG_binding_1, Peptidase_M10~Peptidase_M10, PG_binding_1~Peptidase_M10, PG_binding_1~PG_binding_1
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
and 6 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 582
Hs

1 669
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025