HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: TRRAP (Q9Y4A5)
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)
Gene: TRRAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	31478661
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~Ras
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 3859
+	Hs
		901083 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		545716 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		TRRAP_HUMAN (1-3859): 0: 4445: 100.00
+	Hs
		564441 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787568 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787450 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		787456 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		545244 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		MTOR_HUMAN (2163-3858): 0: 984: 14.90
+	Hs
		893894 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		900371 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		PRKDC_HUMAN (1935-3859): 0: 960: 12.88
+	Hs
		893980 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ATR_HUMAN (2569-3859): 0: 704: 15.07