HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32017888
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0016192 - vesicle-mediated transport GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 1336
+	Hs
		894827 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		JIP3_HUMAN (1-1336): 0: 998: 100.00
+	Hs
		229651 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		JIP4_HUMAN (6-1336): 0: 671: 54.25
+	Hs
		229652 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		JIP4_HUMAN (6-1336): 0: 671: 54.25
+	Hs
		164114 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		ARHGA_HUMAN (913-1292): 8.49e-82: 297: 20.57
+	Hs
		148600 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		148636 RAB1A_HUMAN (1-200): 4.66e-87: 256: 50.24		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		149274 RAB1B_HUMAN (3-200): 5.28e-86: 253: 50.50		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		914124 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		MRCKA_HUMAN (2-407): 2.77e-19: 96.9: 12.93
+	Hs
		148551 RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Sc
		350851 YPT1_YEAST (3-200): 7.2e-90: 263: 50.24		USO1_YEAST (16-448): 2.35e-12: 74.3: 10.62
+	Hs
		254466 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		ROCK2_HUMAN (2-348): 1.31e-13: 78.3: 7.20