HitPredict

Interactor 1: SMC2 (P50533)
Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E)
Gene: SMC2

Interactor 2: CND3L (Q6GN08)
Condensin-2 complex subunit D3-L
Gene: ncapd3.L

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	14532007, 19915589
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cnd1~SMC_N
Common GO terms	GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1203 Xl			1 1492
+	Hs
		333958 SMC2_HUMAN (1-1193): 2.59e-118: 397: 81.14		CNDD3_HUMAN (20-1492): 0: 1909: 58.10
+	Hs
		841263 SMC4_HUMAN (1-1179): 6.12e-85: 304: 16.32		CNDD3_HUMAN (20-1492): 0: 1909: 58.10
+	Xl
		896122 SMC4_XENLA (1-1175): 1.72e-80: 291: 18.03		CND3L_XENLA (1-1492): 0: 1893: 100.00
+	Ce
		1169618 SMC4_CAEEL (1-1167): 3.12e-100: 351: 17.23		CND_CAEEL (445-1416): 0: 769: 21.39
+	Ce
		1068125 MIX1_CAEEL (1-1173): 2.48e-91: 322: 31.16		CND_CAEEL (445-1416): 0: 769: 21.39
+	Hs
		334011 SMC2_HUMAN (1-1193): 2.59e-118: 397: 81.14		CND1_HUMAN (425-1159): 0: 613: 16.77
+	Xl
		896129 SMC2_XENLA (1-1203): 7.49e-124: 413: 100.00		CND1_XENLA (425-1159): 7.14e-169: 546: 15.07
+	Hs
		1137278 SMC4_HUMAN (1-1179): 6.12e-85: 304: 16.32		CND1_HUMAN (425-1159): 0: 613: 16.77
+	Sp
		314700 SMC2_SCHPO (1-1169): 5.79e-101: 349: 36.38		CND1_SCHPO (411-1153): 4.6e-162: 522: 13.74
+	Xl
		896124 SMC4_XENLA (1-1175): 1.72e-80: 291: 18.03		CND1_XENLA (425-1159): 7.14e-169: 546: 15.07
+	Sp
		314701 SMC4_SCHPO (1-1177): 5.55e-85: 305: 17.01		CND1_SCHPO (411-1153): 4.6e-162: 522: 13.74
+	Sc
		808605 SMC2_YEAST (1-1170): 2.5e-91: 321: 35.38		CND1_YEAST (431-1160): 2.92e-149: 488: 14.86
+	Sc
		1053935 SMC4_YEAST (1-1177): 2.15e-62: 236: 15.46		CND1_YEAST (431-1160): 2.92e-149: 488: 14.86
+	Ce
		1169620 SMC4_CAEEL (1-1167): 3.12e-100: 351: 17.23		CND1_CAEEL (805-1102): 2.68e-55: 214: 12.75
+	Dm
		1267236 Q7KK96_DROME (1-1178): 1.02e-94: 331: 42.11		Q9VAJ1_DROME (905-1159): 7.09e-58: 222: 15.41
+	Ce
		1068127 MIX1_CAEEL (1-1173): 2.48e-91: 322: 31.16		CND1_CAEEL (805-1102): 2.68e-55: 214: 12.75
+	Dm
		1463168 Q9V3A7_DROME (1-1171): 8.27e-86: 308: 15.09		Q9VAJ1_DROME (905-1159): 7.09e-58: 222: 15.41
+	Ce
		878246 DPY27_CAEEL (1-1202): 1.68e-75: 276: 15.61		CND1_CAEEL (805-1102): 2.68e-55: 214: 12.75