HitPredict

Interactor 1: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, unassigned3799
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0017124 - SH3 domain binding GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 498
+	Hs
		1279815 SPRE1_HUMAN (2-343): 2.85e-90: 280: 15.66		WASF2_HUMAN (1-498): 1.25e-64: 219: 100.00
+	Hs
		1460153 EVL_HUMAN (1-375): 2.07e-60: 202: 43.68		WASF2_HUMAN (1-498): 1.25e-64: 219: 100.00
+	Hs
		1449331 HOME3_HUMAN (3-294): 6.79e-48: 168: 18.54		WASF2_HUMAN (1-498): 1.25e-64: 219: 100.00
+	Hs
		215909 VASP_HUMAN (1-380): 1.44e-91: 281: 100.00		SYNJ1_HUMAN (41-458): 2.48e-09: 62: 10.54
+	Mm
		1341706 HOME1_MOUSE (1-182): 1.38e-49: 172: 23.78		WASF1_MOUSE (1-496): 6.58e-43: 162: 43.19
+	Dm
		99169 ENA_DROME (2-235): 1.22e-41: 158: 36.33		F2FB81_DROME (1-245): 5.6e-42: 161: 41.53
+	Mm
		1455913 PCLO_MOUSE (95-300): 3.84e-09: 60.8: 13.59		PCLO_MOUSE (102-490): 4.59e-10: 64.7: 10.89
+	Dm
		119660 M9PB30_DROME (83-341): 6.49e-09: 60: 11.89		M9PB30_DROME (78-398): 4.94e-10: 64.7: 13.71