Protein: HOME1
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

Gene: HOME1, Homer1
Organism: Mus musculus
Interactions: 61
UniProt ID: Q9Z2Y3

Gene Ontology (top 5):
GO:0003009 - skeletal muscle contraction
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007216 - G protein-coupled glutamate receptor signaling pathway
GO:0014069 - postsynaptic density

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1194004

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

6

20

Small-scale

0.730

High

104662

SYGP1
Ras/Rap GTPase-activating protein SynGAP

4

12

High-throughput

0.694

High

1190231

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

2

7

High-throughput

0.628

High

1455865

HOME2
Homer protein homolog 2

1

16

Small-scale

0.618

High

1491931

HOME1
Homer protein homolog 1

1

15

Small-scale

0.618

High

972329

1433E
14-3-3 protein epsilon

2

5

High-throughput

0.611

High

990073

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1021862

GRM1
Metabotropic glutamate receptor 1

2

11

Small-scale

0.611

High

1190967

GRM5
Metabotropic glutamate receptor 5

2

11

Small-scale

0.611

High

1424069

DLGP1
Disks large-associated protein 1

2

4

High-throughput

0.611

High

1223789

DLG4
Disks large homolog 4

2

9

High-throughput

0.584

High

1247259

NEB2
Neurabin-2

2

20

High-throughput

0.584

High

59353

LZTS3
Leucine zipper putative tumor suppressor 3

1

18

High-throughput

0.536

High

60128

KALRN
Kalirin

1

20

High-throughput

0.536

High

92689

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

20

High-throughput

0.536

High

147433

BIN1
Myc box-dependent-interacting protein 1

1

11

High-throughput

0.536

High

148528

CYH3
Cytohesin-3

1

2

High-throughput

0.536

High

564881

NCAM1
Neural cell adhesion molecule 1

1

6

High-throughput

0.536

High

607855

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.536

High

632523

KPCA
Protein kinase C alpha type

1

6

High-throughput

0.536

High

771514

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

6

High-throughput

0.536

High

810543

DYN1
Dynamin-1

1

2

High-throughput

0.536

High

993988

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

7

High-throughput

0.536

High

999295

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1013730

TNIK
Traf2 and NCK-interacting protein kinase

1

12

High-throughput

0.536

High

1021903

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

3

High-throughput

0.536

High

1223387

MYH10
Myosin-10

1

7

High-throughput

0.536

High

1223959

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.536

High

1229323

Q68FG2
Spectrin beta chain

1

20

High-throughput

0.536

High

1229943

CNTN4
Contactin-4

1

1

High-throughput

0.536

High

1283071

MYOME
Myomegalin

1

15

High-throughput

0.536

High

1283099

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

20

High-throughput

0.536

High

1297585

TENR
Tenascin-R

1

6

High-throughput

0.536

High

1341706

WASF1
Actin-binding protein WASF1

1

10

High-throughput

0.536

High

548980

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.513

High

1491890

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

1491893

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.513

High

204245

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

10

High-throughput

0.489

High

1423752

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.489

High

108968

G3X9H5
Huntingtin

1

5

High-throughput

0.479

High

205162

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.479

High

530954

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.479

High

549518

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

7

Small-scale

0.479

High

915374

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

5

High-throughput

0.479

High

1029256

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

6

High-throughput

0.479

High

1189997

Q3UCL2
E3 ubiquitin-protein ligase TRIM21

1

7

High-throughput

0.479

High

1221895

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.479

High

1223173

GRID2
Glutamate receptor ionotropic, delta-2

1

6

Small-scale

0.479

High

1021677

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.458

High

1362167

Q91UZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

1

0

Small-scale

0.458

High

597668

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.445

High

1223888

RO52
E3 ubiquitin-protein ligase TRIM21

1

7

High-throughput

0.445

High

1341486

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.445

High

1424355

CSTN1
Calsyntenin-1

1

7

Small-scale

0.445

High

1455861

SRCN1
SRC kinase signaling inhibitor 1

1

3

High-throughput

0.445

High

59198

A2A9M5
Dedicator of cytokinesis 7

1

2

High-throughput

0.437

High

86367

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.437

High

1296502

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

12

High-throughput

0.437

High

1298156

Q8C845
EF hand domain containing 2

1

3

High-throughput

0.437

High

1424160

EFHD2
EF-hand domain-containing protein D2

1

3

High-throughput

0.407

High


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Last updated: 11Aug2025