Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 21653829
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0017124 - SH3 domain binding
GO:0043005 - neuron projection
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 870
Hs

1 1806
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025