Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: CSN4 (Q9BT78)
COP9 signalosome complex subunit 4 (SGN4) (Signalosome subunit 4) (JAB1-containing signalosome subunit 4)
Gene: COPS4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 32034103, 24981860, 19295130, 26186194, 28514442, 27173435, 31444342, 33961781, 37071682, 16045761
Identification Methods pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN4_RPN5_eIF3a~PCI, PCI~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 443
Hs

1 406
+ Mm
+ Dm
+ Mm
+ Hs
+ Hs
+ Dm
+ At
+ Ce
+ An
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Sc
+ Dm
+ Ce
+ At
+ Sp
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024