HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (EC 3.6.1.-) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 32296183, 30021884, 24981860, 35271311, 37071682, 35575683, 28524877, 38334954, 39358380, 31839598, 33961781, 35366418, 35235311, 34349018, 36652389, 39422127, 26414014, 40437099, unassigned1304
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, cross-linking study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0002199 - zona pellucida receptor complex
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 539
Hs

1 535
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+ Bt
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+ Ph
+ Dm
+ Hs
+ At
+ Ce
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+ Bt
+ Dm

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Last updated: 11Aug2025