HitPredict

Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 621 Hs			1 2229
+	Hs
		900363 FXR2_HUMAN (4-621): 0: 840: 57.75		PRC2B_HUMAN (1-2229): 0: 638: 100.00
+	Mm
		1223040 FXR1_MOUSE (1-621): 0: 950: 88.77		PRC2B_MOUSE (1-1464): 5.63e-73: 273: 48.79
+	Hs
		900153 FXR1_HUMAN (1-621): 0: 998: 100.00		TARA_HUMAN (34-1668): 2.8e-34: 147: 8.75
+	Hs
		899896 FXR1_HUMAN (1-621): 0: 998: 100.00		EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63
+	Hs
		900244 FXR1_HUMAN (1-621): 0: 998: 100.00		PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67
+	Hs
		875591 FXR1_HUMAN (1-621): 0: 998: 100.00		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67
+	Hs
		334282 FXR1_HUMAN (1-621): 0: 998: 100.00		TACC2_HUMAN (1484-2228): 4.7e-09: 64.3: 8.45
+	Mm
		1223041 FXR1_MOUSE (1-621): 0: 950: 88.77		PRC2A_MOUSE (41-1257): 5.33e-17: 90.5: 8.29
+	Mm
		1189497 FXR1_MOUSE (1-621): 0: 950: 88.77		PRC2C_MOUSE (8-1010): 5.43e-11: 70.9: 6.86
+	Hs
		900505 FXR2_HUMAN (4-621): 0: 840: 57.75		TARA_HUMAN (34-1668): 2.8e-34: 147: 8.75
+	Hs
		900573 FXR2_HUMAN (4-621): 0: 840: 57.75		PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67
+	Hs
		875592 FXR2_HUMAN (4-621): 0: 840: 57.75		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67
+	Mm
		1274471 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		PRC2B_MOUSE (1-1464): 5.63e-73: 273: 48.79
+	Mm
		777941 FMR1_MOUSE (1-506): 0: 599: 51.04		PRC2B_MOUSE (1-1464): 5.63e-73: 273: 48.79
+	Mm
		1235705 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		NIPBL_MOUSE (85-1151): 1.2e-18: 96: 12.39
+	Mm
		1274604 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		PRC2A_MOUSE (41-1257): 5.33e-17: 90.5: 8.29
+	Mm
		777919 FMR1_MOUSE (1-506): 0: 599: 51.04		NIPBL_MOUSE (85-1151): 1.2e-18: 96: 12.39
+	Mm
		777943 FMR1_MOUSE (1-506): 0: 599: 51.04		PRC2A_MOUSE (41-1257): 5.33e-17: 90.5: 8.29
+	Mm
		1189501 Q8BPK8_MOUSE (1-334): 0: 618: 73.95		PRC2C_MOUSE (8-1010): 5.43e-11: 70.9: 6.86
+	Mm
		777872 FMR1_MOUSE (1-506): 0: 599: 51.04		PRC2C_MOUSE (8-1010): 5.43e-11: 70.9: 6.86