HitPredict

Interactor 1: VA0D1 (P61421)
V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Gene: ATP6V0D1

Interactor 2: VPP3 (Q13488)
V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)
Gene: TCIRG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 28514442
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~vATP-synt_AC39
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016324 - apical plasma membrane
and 4 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 351
Hs

1 830
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Last updated: 15 Jul 2024