HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19944695
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030054 - cell junction GO:0098794 - postsynapse GO:1901224 - positive regulation of non-canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 404
+	Hs
		793252 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		793262 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		436192 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		793271 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		793248 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		545250 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		793246 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		793258 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		MUC18_HUMAN (22-301): 1.39e-58: 203: 24.92
+	Hs
		894276 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PXDN_HUMAN (172-403): 7.12e-25: 109: 13.42
+	Hs
		901110 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ROBO1_HUMAN (232-401): 5.96e-17: 85.4: 15.96
+	Hs
		892359 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		CD166_HUMAN (19-390): 2.24e-22: 101: 17.71
+	Hs
		925776 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ROBO1_HUMAN (232-401): 5.96e-17: 85.4: 15.96
+	Hs
		915663 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		CD166_HUMAN (19-390): 2.24e-22: 101: 17.71
+	Hs
		436602 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ROBO1_HUMAN (232-401): 5.96e-17: 85.4: 15.96
+	Hs
		894644 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ROBO1_HUMAN (232-401): 5.96e-17: 85.4: 15.96
+	Ce
		136793 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		UNC89_CAEEL (236-364): 4.41e-12: 70.4: 15.94
+	Ce
		104464 G5EBV3_CAEEL (2-193): 1.08e-77: 232: 50.52		UNC89_CAEEL (236-364): 4.41e-12: 70.4: 15.94
+	Hs
		894044 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		MYLK_HUMAN (17-117): 2.21e-12: 71.2: 14.85
+	Ce
		136800 RHO1_CAEEL (1-192): 2.25e-75: 226: 85.94		UNC89_CAEEL (236-364): 4.41e-12: 70.4: 15.94
+	Ce
		136794 CDC42_CAEEL (1-193): 2.41e-74: 223: 50.78		UNC89_CAEEL (236-364): 4.41e-12: 70.4: 15.94