Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: PKN2 (Q16513)
Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)
Gene: PKN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.944

The method score is based on:

Property Details
Experiments 9446575, 28514442, 8910519, 33961781, 31871319, 34591642
Identification Methods far western blotting, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HR1~Ras, Pkinase~Ras
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030027 - lamellipodium
GO:0030496 - midbody
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 193
Hs

1 984
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024