HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: BACD1 (Q8WZ19)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (hBACURD1) (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1) (TNFAIP1-like protein)
Gene: KCTD13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	19782033, 26100637
Identification Methods	pull down, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016477 - cell migration GO:0043149 - stress fiber assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 329
+	Hs
		900457 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		BACD2_HUMAN (23-329): 7.29e-132: 379: 64.50
+	Hs
		915665 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		BACD2_HUMAN (23-329): 7.29e-132: 379: 64.50
+	Hs
		915969 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		BACD3_HUMAN (11-324): 1.53e-119: 348: 67.41
+	Hs
		894625 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		KCTD3_HUMAN (24-170): 9.36e-41: 153: 24.32
+	Hs
		925437 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		KCD17_HUMAN (41-192): 1.02e-40: 146: 28.93
+	Hs
		925453 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		SHKB1_HUMAN (23-143): 9.04e-28: 115: 31.97
+	Hs
		894236 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		SHKB1_HUMAN (23-143): 9.04e-28: 115: 31.97
+	Hs
		545512 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		SHKB1_HUMAN (23-143): 9.04e-28: 115: 31.97