HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ARAP2 (Q8WZ64)
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX)
Gene: ARAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	32203420
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Ras, RA~Ras, Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1704
+	Hs
		925478 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ARAP2_HUMAN (1-1704): 0: 1808: 100.00
+	Hs
		925529 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ARAP1_HUMAN (476-1586): 0: 791: 40.30
+	Hs
		901056 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		AGAP1_HUMAN (361-914): 2.07e-110: 374: 17.98
+	Hs
		901000 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG23_HUMAN (863-1668): 3.87e-104: 369: 14.32
+	Ce
		88245 RAC1_CAEEL (1-193): 2.07e-80: 238: 55.44		D3YT54_CAEEL (1073-1670): 7.72e-101: 339: 14.29
+	Hs
		925420 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG12_HUMAN (746-1298): 7.69e-97: 335: 17.14
+	Hs
		302639 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		FA13A_HUMAN (1101-1669): 2.05e-86: 308: 14.14
+	Hs
		900834 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		AGAP2_HUMAN (414-942): 1.07e-84: 306: 17.04
+	Hs
		925378 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG27_HUMAN (873-1298): 5.3e-86: 304: 17.61
+	Hs
		64681 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG32_HUMAN (1029-1446): 2.99e-77: 287: 18.20
+	Hs
		64688 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG32_HUMAN (1029-1446): 2.99e-77: 287: 18.20
+	Mm
		925803 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG32_MOUSE (1029-1446): 2.82e-77: 287: 18.43
+	Hs
		925329 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG15_HUMAN (907-1302): 1.05e-83: 285: 17.89
+	Hs
		900747 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		STAR8_HUMAN (1108-1533): 2.6e-77: 281: 13.49
+	Hs
		551044 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIN_HUMAN (1107-1297): 3.11e-67: 237: 24.50
+	Mm
		925802 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		CHIO_MOUSE (1107-1297): 1.94e-66: 230: 23.50
+	Hs
		856140 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		CHIO_HUMAN (1107-1297): 4.66e-64: 228: 23.50
+	Hs
		900564 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		RHG21_HUMAN (388-648): 1.49e-17: 91.6: 12.23
+	Hs
		925343 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RHG21_HUMAN (388-648): 1.49e-17: 91.6: 12.23
+	Mm
		925805 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		RHG22_MOUSE (445-573): 2.88e-17: 90.1: 13.70