Protein: TPD54
Tumor protein D54 (hD54) (Tumor protein D52-like 2)

Gene: TPD54, TPD52L2
Organism: Homo sapiens
Interactions: 104
UniProt ID: O43399

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005975 - carbohydrate metabolic process
GO:0042127 - regulation of cell population proliferation
GO:0042803 - protein homodimerization activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

215408

TPD52
Tumor protein D52

4

14

Small-scale

0.697

High

215428

TPD53
Tumor protein D53

4

14

Small-scale

0.697

High

215445

TPD55
Tumor protein D55

3

14

Small-scale

0.656

High

215458

SHLB1
Endophilin-B1

3

3

High-throughput

0.654

High

215375

RASK
GTPase KRas

3

9

High-throughput

0.640

High

215443

CSN5
COP9 signalosome complex subunit 5

3

0

High-throughput

0.638

High

215407

TERA
Transitional endoplasmic reticulum ATPase

3

1

High-throughput

0.633

High

215420

GABP1
GA-binding protein subunit beta-1

3

2

High-throughput

0.609

High

215459

RT02
Small ribosomal subunit protein uS2m

3

1

High-throughput

0.609

High

215365

TPD54
Tumor protein D54

2

14

Small-scale

0.600

High

215389

RAB4A
Ras-related protein Rab-4A

2

8

High-throughput

0.584

High

215412

ARF6
ADP-ribosylation factor 6

2

2

High-throughput

0.584

High

215419

GABPA
GA-binding protein alpha chain

2

1

High-throughput

0.574

High

215446

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

2

Small-scale

0.573

High

215378

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.541

High

215403

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.536

High

215373

RASN
GTPase NRas

2

9

High-throughput

0.533

High

215413

RB11A
Ras-related protein Rab-11A

2

5

High-throughput

0.533

High

215406

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

215410

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.501

High

215367

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

2

High-throughput

0.489

High

215416

HTRA4
Serine protease HTRA4

1

1

High-throughput

0.489

High

215436

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

1

High-throughput

0.489

High

215461

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.489

High

175812

SET1A
Histone-lysine N-methyltransferase SETD1A

1

2

High-throughput

0.479

High

215374

RASH
GTPase HRas

1

6

High-throughput

0.479

High

215381

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

215382

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

215383

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

215386

ANPRC
Atrial natriuretic peptide receptor 3

1

1

High-throughput

0.479

High

215387

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

215388

RAB3B
Ras-related protein Rab-3B

1

4

High-throughput

0.479

High

215390

RAB5A
Ras-related protein Rab-5A

1

6

High-throughput

0.479

High

215391

1433T
14-3-3 protein theta

1

10

Small-scale

0.479

High

215394

PML
Protein PML

1

1

High-throughput

0.479

High

215397

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

215421

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.479

High

215425

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.479

High

215427

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

215432

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

215437

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.479

High

215439

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

215442

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

215449

RAB1B
Ras-related protein Rab-1B

1

4

High-throughput

0.479

High

215456

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.479

High

215457

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

215460

ARL5A
ADP-ribosylation factor-like protein 5A

1

3

High-throughput

0.479

High

189324

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

215371

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

215372

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

215376

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

215379

S10A6
Protein S100-A6

1

0

Small-scale

0.458

High

215395

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

215398

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

215402

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

215418

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

215422

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.458

High

215453

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

215454

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

215455

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

215377

PRIO
Major prion protein

1

1

High-throughput

0.445

High

215452

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

104886

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

215366

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

215370

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.437

High

215385

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

215392

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

215401

CENPA
Histone H3-like centromeric protein A

1

1

High-throughput

0.437

High

215404

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.437

High

215405

RAB9A
Ras-related protein Rab-9A

1

7

High-throughput

0.437

High

215409

RAB25
Ras-related protein Rab-25

1

5

High-throughput

0.437

High

215411

RAB2A
Ras-related protein Rab-2A

1

7

High-throughput

0.437

High

215414

RHOB
Rho-related GTP-binding protein RhoB

1

3

High-throughput

0.437

High

215417

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.437

High

215423

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

215426

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.437

High

215431

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

215433

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

215434

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

215435

SDCG8
Serologically defined colon cancer antigen 8

1

1

High-throughput

0.437

High

215441

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.437

High

215450

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.437

High

215384

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

215415

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.426

High

187229

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

0

High-throughput

0.328

High

215438

COQ8A
Atypical kinase COQ8A, mitochondrial

2

0

High-throughput

0.316

High

215440

ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5

2

0

High-throughput

0.316

High

215393

AA2BR
Adenosine receptor A2b

1

0

High-throughput

0.282

High

215447

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

215451

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

139771

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

210511

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.249

Low

215368

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.249

Low

215369

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

215380

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

215396

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.249

Low

215400

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

215424

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

215430

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

215399

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low

215429

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

215444

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

215448

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025