HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: RTKN (Q9BST9)
Rhotekin
Gene: RTKN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.984

Property	Details
Experiments	26825171, 31871319, 19696020, 14749388, 22693251, 19147496, 12593858, 27775029, 19805522, 15075243, 25150978, 34591642, 12879077, 19944695, 18256687, 22621765, 22705156
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005525 - GTP binding GO:0005829 - cytosol GO:0007266 - Rho protein signal transduction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 563
+	Hs
		925570 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Hs
		436482 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Mm
		1207978 RHOA_MOUSE (1-193): 4.1e-81: 240: 99.48		RTKN_MOUSE (1-563): 0: 1036: 86.70
+	Hs
		915929 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		RTKN_HUMAN (1-563): 0: 1053: 100.00
+	Rn
		901291 RHOA_RAT (1-193): 4.1e-81: 240: 99.48		RTKN_RAT (37-563): 0: 959: 87.50
+	Hs
		436397 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		RTKN2_HUMAN (37-486): 0: 730: 42.64
+	Hs
		915820 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		RTKN2_HUMAN (37-486): 0: 730: 42.64