HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: TYW1 (Q9NV66)
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein)
Gene: TYW1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 732
+	Hs
		951387 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		TYW1_HUMAN (1-732): 0: 1128: 100.00
+	Hs
		894493 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		TYW1_HUMAN (1-732): 0: 1128: 100.00
+	Hs
		545647 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		TYW1_HUMAN (1-732): 0: 1128: 100.00
+	Hs
		560184 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560186 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		436146 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560188 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560182 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		545195 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560181 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		120297 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		718483 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NOS2_HUMAN (8-351): 5.24e-52: 197: 17.25
+	Hs
		545231 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		NOS2_HUMAN (8-351): 5.24e-52: 197: 17.25
+	Mm
		667784 RAC1_MOUSE (1-193): 8.86e-80: 237: 57.22		NOS2_MOUSE (8-246): 5.8e-47: 182: 18.70
+	Mm
		667792 RAC2_MOUSE (1-193): 1.45e-75: 226: 53.09		NOS2_MOUSE (8-246): 5.8e-47: 182: 18.70