HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: HACD3 (Q9P035)
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)
Gene: HACD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005925 - focal adhesion GO:0007266 - Rho protein signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 362
+	Hs
		925679 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		436547 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		894526 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		545665 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		892640 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		916032 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		120681 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		HACD3_HUMAN (1-362): 1.85e-148: 425: 100.00
+	Hs
		900609 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		HACD2_HUMAN (138-355): 2.41e-85: 260: 26.15
+	Hs
		545457 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		HACD2_HUMAN (138-355): 2.41e-85: 260: 26.15
+	Hs
		892444 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		HACD2_HUMAN (138-355): 2.41e-85: 260: 26.15