HitPredict

Interactor 1: NAA20 (P61599)
N-alpha-acetyltransferase 20 (EC 2.3.1.254) (Methionine N-acetyltransferase) (N-acetyltransferase 5) (N-terminal acetyltransferase B complex catalytic subunit NAA20) (N-terminal acetyltransferase B complex catalytic subunit NAT5) (NatB complex subunit NAT5) (NatB catalytic subunit)
Gene: NAA20

Interactor 2: NAA25 (Q14CX7)
N-alpha-acetyltransferase 25, NatB auxiliary subunit (Mitochondrial distribution and morphology protein 20) (N-terminal acetyltransferase B complex subunit MDM20) (NatB complex subunit MDM20) (N-terminal acetyltransferase B complex subunit NAA25) (p120)
Gene: NAA25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	18570629
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Acetyltransf_1~NatB_MDM20
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031416 - NatB complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 972
+	Dm
		116294 M9PI14_DROME (1-177): 4.53e-67: 204: 67.23		NAA25_DROME (12-728): 0: 626: 35.65
+	Ce
		1094552 Q965S3_CAEEL (1-178): 2.54e-59: 184: 60.11		NAA25_CAEEL (12-710): 0: 565: 27.43
+	Mm
		102622 NAA10_MOUSE (3-162): 5.41e-58: 183: 31.48		G3X8Y3_MOUSE (10-524): 1.55e-127: 409: 12.22
+	Hs
		782289 NAA10_HUMAN (3-162): 2.31e-58: 184: 31.48		NAA15_HUMAN (10-524): 1.71e-127: 408: 12.39
+	Hs
		1311627 NAA11_HUMAN (3-162): 3.65e-57: 180: 33.33		NAA15_HUMAN (10-524): 1.71e-127: 408: 12.39
+	Hs
		1315323 NAA50_HUMAN (2-160): 4.83e-47: 152: 20.00		NAA15_HUMAN (10-524): 1.71e-127: 408: 12.39
+	Sc
		987595 NAT3_YEAST (1-173): 7.64e-49: 158: 40.61		NAA25_YEAST (16-697): 4.9e-122: 392: 18.79
+	Dm
		1373874 Q9VT75_DROME (3-176): 3.95e-61: 189: 31.64		Q9VWI2_DROME (10-537): 1.78e-107: 356: 11.56
+	Hs
		782253 NAA10_HUMAN (3-162): 2.31e-58: 184: 31.48		NAA16_HUMAN (10-527): 1.45e-106: 352: 11.11
+	Hs
		1154519 NAA11_HUMAN (3-162): 3.65e-57: 180: 33.33		NAA16_HUMAN (10-527): 1.45e-106: 352: 11.11
+	Ca
		1124236 Q5AAR6_CANAL (1-166): 1.35e-52: 167: 42.78		Q5AB99_CANAL (13-674): 8.73e-110: 358: 19.37
+	Dm
		1342125 SAN_DROME (2-164): 1.21e-47: 155: 19.51		Q9VWI2_DROME (10-537): 1.78e-107: 356: 11.56
+	Hs
		1154521 NAA50_HUMAN (2-160): 4.83e-47: 152: 20.00		NAA16_HUMAN (10-527): 1.45e-106: 352: 11.11
+	Sp
		251650 YCPD_SCHPO (1-132): 1.88e-26: 99.7: 16.30		NAT1_SCHPO (10-525): 6.23e-84: 288: 12.39
+	Sc
		427336 ARD1_YEAST (2-157): 2.34e-40: 138: 27.27		NAT1_YEAST (11-359): 5.54e-65: 237: 12.02
+	Sc
		523316 NAT5_YEAST (3-157): 6.29e-31: 112: 14.04		NAT1_YEAST (11-359): 5.54e-65: 237: 12.02