HitPredict

Interactor 1: NCALD (P61601)
Neurocalcin-delta
Gene: NCALD

Interactor 2: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	32296183, unassigned1304, 32814053
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 444
+	Hs
		740670 HPCL1_HUMAN (1-193): 3.61e-60: 187: 90.67		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		917031 VISL1_HUMAN (1-189): 5.08e-49: 159: 67.02		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1191592 KCIP2_HUMAN (8-185): 1.36e-47: 158: 42.70		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1191628 HPCL4_HUMAN (1-189): 1.08e-48: 158: 64.40		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		917030 VISL1_HUMAN (1-189): 5.08e-49: 159: 67.02		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		906770 NCS1_HUMAN (1-185): 1.53e-47: 155: 60.00		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		1191414 KCIP1_HUMAN (2-185): 4.18e-43: 145: 40.22		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		208415 VISL1_HUMAN (1-189): 5.08e-49: 159: 67.02		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79