Interactor 1: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Interactor 2: Q95J06 (Q95J06)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen) (MHC class I protein) (MHC leukocyte antigen) (Major histocompatibility complex, class I, A)
Gene: HLA-A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27649529
Identification Methods surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0005615 - extracellular space
GO:0009897 - external side of plasma membrane
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0030670 - phagocytic vesicle membrane
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 119
Hs

1 365
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024