HitPredict

Interactor 1: H3 (P61830)
Histone H3
Gene: HHT1

Interactor 2: YL455 (Q06188)
PWWP domain-containing protein YLR455W
Gene: YLR455W

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.924

Property	Details
Experiments	25104842, 25473596, 37968396, 33010166, 22199229
Identification Methods	affinity chromatography technology, pull down, unspecified method, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Sc			1 304
+	Hs
		934827 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		GLYR1_HUMAN (4-184): 2.55e-64: 213: 19.02
+	Hs
		952374 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		GLYR1_HUMAN (4-184): 2.55e-64: 213: 19.02
+	Hs
		1086171 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		GLYR1_HUMAN (4-184): 2.55e-64: 213: 19.02
+	Hs
		828247 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		GLYR1_HUMAN (4-184): 2.55e-64: 213: 19.02
+	Hs
		331780 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		NSD2_HUMAN (3-159): 1.74e-11: 66.8: 13.29
+	Hs
		331787 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		NSD2_HUMAN (3-159): 1.74e-11: 66.8: 13.29
+	Hs
		935205 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		NSD3_HUMAN (5-199): 4.82e-11: 65.7: 15.24
+	Hs
		331823 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		NSD2_HUMAN (3-159): 1.74e-11: 66.8: 13.29
+	Hs
		952607 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		NSD3_HUMAN (5-199): 4.82e-11: 65.7: 15.24
+	Hs
		331833 H32_HUMAN (1-136): 6.6e-61: 185: 88.97		NSD2_HUMAN (3-159): 1.74e-11: 66.8: 13.29
+	Hs
		1086307 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		NSD3_HUMAN (5-199): 4.82e-11: 65.7: 15.24
+	Hs
		935129 H31_HUMAN (1-136): 3.24e-62: 188: 88.97		NSD1_HUMAN (9-119): 3e-10: 63.4: 19.47
+	Hs
		952555 H33_HUMAN (1-136): 1.25e-61: 187: 90.44		NSD1_HUMAN (9-119): 3e-10: 63.4: 19.47
+	Hs
		1086280 H31T_HUMAN (1-136): 1.96e-61: 186: 86.03		NSD1_HUMAN (9-119): 3e-10: 63.4: 19.47
+	Hs
		1157224 H3C_HUMAN (1-136): 8.2e-59: 179: 86.03		NSD3_HUMAN (5-199): 4.82e-11: 65.7: 15.24
+	Hs
		331748 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		NSD2_HUMAN (3-159): 1.74e-11: 66.8: 13.29
+	Hs
		828367 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		NSD3_HUMAN (5-199): 4.82e-11: 65.7: 15.24
+	Hs
		828350 CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73		NSD1_HUMAN (9-119): 3e-10: 63.4: 19.47