HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 360
+	Hs
		903349 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5B_HUMAN (78-360): 5.47e-51: 174: 17.31
+	Hs
		903418 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		903551 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		NLE1_HUMAN (210-358): 6.14e-32: 126: 15.58
+	Hs
		282871 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		CIAO1_HUMAN (57-321): 2.68e-22: 98: 20.71
+	Hs
		903428 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		903077 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		792949 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		LIS1_HUMAN (272-360): 7.69e-17: 83: 16.85
+	Hs
		878165 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Hs
		1240442 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		POC1A_HUMAN (98-359): 1.13e-51: 178: 13.36
+	Hs
		282843 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		CIAO1_HUMAN (57-321): 2.68e-22: 98: 20.71
+	Hs
		792935 LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49		LIS1_HUMAN (272-360): 7.69e-17: 83: 16.85
+	Mm
		925836 LIS1_MOUSE (2-289): 1.02e-94: 288: 29.49		LIS1_MOUSE (272-360): 6.81e-17: 83: 16.85
+	Hs
		209467 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Dm
		1358845 WDS_DROME (3-290): 7.53e-92: 279: 31.21		WDS_DROME (265-360): 3.21e-17: 83.7: 16.67
+	Hs
		209416 PLRG1_HUMAN (2-333): 5.29e-85: 267: 26.05		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		1288273 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		1103007 SMU1_HUMAN (30-331): 7.66e-39: 145: 28.71		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Sc
		630844 NLE1_YEAST (167-333): 3.95e-41: 152: 23.70		NLE1_YEAST (3-86): 1.94e-16: 82.2: 22.62