HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25666610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0072686 - mitotic spindle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 914
+	Hs
		1288311 SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		903416 WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		1231083 POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		1273271 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		1191352 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		ARHG8_HUMAN (364-737): 9.34e-77: 263: 23.00
+	Hs
		1299212 WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		1266889 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		TOPB1_HUMAN (92-458): 8.82e-90: 314: 23.10
+	Hs
		1049720 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHG7_HUMAN (309-913): 4.64e-90: 305: 11.83
+	Hs
		1016930 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		AKP13_HUMAN (274-912): 7.43e-83: 295: 13.83
+	Hs
		1254029 NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54		PREX1_HUMAN (406-861): 1.32e-78: 282: 18.47
+	Hs
		1273255 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		164142 FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15		ARHGA_HUMAN (436-704): 1.71e-23: 109: 29.33