HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: RBM10 (P98175)
RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)
Gene: RBM10

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 930
+	Hs
		958035 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		RBM10_HUMAN (1-930): 2.52e-168: 516: 100.00
+	Hs
		516439 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		PABP1_HUMAN (11-289): 5.49e-21: 100: 10.35
+	Mm
		665747 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		PABP1_MOUSE (11-289): 6.54e-21: 100: 10.35
+	Hs
		903955 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		ELAV1_HUMAN (289-448): 4.76e-20: 94.2: 18.41
+	Mm
		904236 HNRPK_MOUSE (1-463): 1.31e-129: 385: 100.00		ELAV1_MOUSE (289-448): 8.56e-20: 93.4: 19.02
+	Mm
		888827 PCBP1_MOUSE (23-127): 3.42e-12: 69.7: 23.15		RBM47_MOUSE (126-536): 3.57e-58: 212: 12.71
+	Hs
		47757 PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24		RBM47_HUMAN (126-536): 4.02e-57: 209: 12.97
+	Hs
		47779 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		RBM47_HUMAN (126-536): 4.02e-57: 209: 12.97
+	Hs
		47908 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		RBM47_HUMAN (126-536): 4.02e-57: 209: 12.97
+	Hs
		1273078 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		A1CF_HUMAN (77-595): 1.63e-56: 207: 11.43
+	Hs
		47843 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		RBM47_HUMAN (126-536): 4.02e-57: 209: 12.97
+	Hs
		941815 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		RBM6_HUMAN (572-930): 5.8e-50: 193: 32.03
+	Hs
		1031509 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP4_HUMAN (11-324): 1.48e-24: 111: 11.59
+	Hs
		516531 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		PABP1_HUMAN (11-289): 5.49e-21: 100: 10.35
+	Hs
		516530 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		PABP1_HUMAN (11-289): 5.49e-21: 100: 10.35
+	Hs
		516769 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		PABP1_HUMAN (11-289): 5.49e-21: 100: 10.35
+	Hs
		516642 FUBP3_HUMAN (331-457): 1.39e-11: 68.5: 24.41		PABP1_HUMAN (11-289): 5.49e-21: 100: 10.35
+	Hs
		1020359 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		ELAV2_HUMAN (289-455): 3.93e-21: 98: 16.17
+	Hs
		1077440 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		ELAV1_HUMAN (289-448): 4.76e-20: 94.2: 18.41
+	Hs
		1077550 IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00		ELAV1_HUMAN (289-448): 4.76e-20: 94.2: 18.41