Protein: TAP2
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)

Gene: TAP2
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q03519

Gene Ontology (top 5):
GO:0001913 - T cell mediated cytotoxicity
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002237 - response to molecule of bacterial origin
GO:0002481 - antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

976712

TAP1
Antigen peptide transporter 1

12

15

Small-scale

0.978

High

529008

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.691

High

976780

TAP2
Antigen peptide transporter 2

1

14

Small-scale

0.647

High

134651

NPT3
Sodium-dependent phosphate transport protein 3

2

1

High-throughput

0.628

High

182269

TPSN
Tapasin

2

6

Small-scale

0.624

High

976804

RN185
E3 ubiquitin-protein ligase RNF185

2

4

Small-scale

0.611

High

845997

SCNND
Amiloride-sensitive sodium channel subunit delta

2

0

High-throughput

0.602

High

976795

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.602

High

382397

HLAA
HLA class I histocompatibility antigen, A alpha chain

2

8

Small-scale

0.584

High

802319

5HT3A
5-hydroxytryptamine receptor 3A

2

4

High-throughput

0.574

High

171980

GP182
G-protein coupled receptor 182

1

11

High-throughput

0.536

High

173276

S22A2
Solute carrier family 22 member 2

1

6

High-throughput

0.536

High

245227

RAMP2
Receptor activity-modifying protein 2

1

3

High-throughput

0.536

High

274730

RA51D
DNA repair protein RAD51 homolog 4

1

1

High-throughput

0.536

High

310608

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.536

High

513737

CP19A
Aromatase

1

1

High-throughput

0.536

High

558717

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

5

High-throughput

0.536

High

654275

CALX
Calnexin

1

4

High-throughput

0.536

High

736143

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

2

High-throughput

0.536

High

976782

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

5

High-throughput

0.536

High

976783

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

2

High-throughput

0.536

High

976786

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

1

High-throughput

0.536

High

976787

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.536

High

976788

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

976790

PTHD3
Patched domain-containing protein 3

1

4

High-throughput

0.536

High

976792

TTMP
TPA-induced transmembrane protein

1

3

High-throughput

0.536

High

976793

ATLA3
Atlastin-3

1

1

High-throughput

0.536

High

976799

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.536

High

976803

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

3

High-throughput

0.536

High

976806

GWL
Serine/threonine-protein kinase greatwall

1

1

High-throughput

0.536

High

976809

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.536

High

976814

RXFP1
Relaxin receptor 1

1

2

High-throughput

0.536

High

976820

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

2

High-throughput

0.536

High

533141

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

8

Small-scale

0.515

High

217308

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

957979

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

0

High-throughput

0.513

High

976801

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

976823

ZN281
Zinc finger protein 281

1

0

High-throughput

0.513

High

394575

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

362135

ACHA
Acetylcholine receptor subunit alpha

1

2

High-throughput

0.489

High

380371

CD3D
T-cell surface glycoprotein CD3 delta chain

1

1

High-throughput

0.489

High

813935

GPR12
G-protein coupled receptor 12

1

5

High-throughput

0.489

High

856599

EFNA5
Ephrin-A5

1

1

High-throughput

0.489

High

976784

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

9

High-throughput

0.489

High

976785

KLRD1
Natural killer cells antigen CD94

1

9

High-throughput

0.489

High

976796

LRC55
Leucine-rich repeat-containing protein 55

1

3

High-throughput

0.489

High

976798

TMM25
Transmembrane protein 25

1

1

High-throughput

0.489

High

976815

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.489

High

976817

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

3

High-throughput

0.489

High

976821

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

1

High-throughput

0.489

High

976822

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

2

High-throughput

0.489

High

976824

PTC2
Protein patched homolog 2

1

4

High-throughput

0.489

High

227225

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

266146

ERLN1
Erlin-1

1

1

Small-scale

0.479

High

299882

ERLN2
Erlin-2

1

2

Small-scale

0.479

High

314865

FMNL1
Formin-like protein 1

1

2

Small-scale

0.479

High

393170

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

6

Small-scale

0.479

High

488198

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

8

Small-scale

0.479

High

561559

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

6

Small-scale

0.479

High

570322

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

8

Small-scale

0.479

High

668615

PML
Protein PML

1

1

High-throughput

0.479

High

874845

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

901863

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

15

Small-scale

0.479

High

976808

RNF5
E3 ubiquitin-protein ligase RNF5

1

3

Small-scale

0.479

High

976812

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.479

High

976816

DJB12
DnaJ homolog subfamily B member 12

1

3

Small-scale

0.479

High

976819

AMFR
E3 ubiquitin-protein ligase AMFR

1

2

Small-scale

0.479

High

656055

PSB8
Proteasome subunit beta type-8

1

5

Small-scale

0.464

High

976800

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

Small-scale

0.458

High

976802

FAF2
FAS-associated factor 2

1

0

Small-scale

0.458

High

976818

DJB11
DnaJ homolog subfamily B member 11

1

0

Small-scale

0.458

High

354425

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

8

High-throughput

0.445

High

205296

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

501040

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.437

High

940807

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

976781

TF65
Transcription factor p65

1

3

Small-scale

0.437

High

976789

P2RY6
P2Y purinoceptor 6

1

14

High-throughput

0.437

High

976794

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

976797

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

976805

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

976813

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

656109

PSB9
Proteasome subunit beta type-9

1

5

Small-scale

0.417

High

976807

RBM18
Probable RNA-binding protein 18

1

0

High-throughput

0.282

High

976810

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.282

High

976791

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

976811

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

Small-scale

0.275

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024