HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005925 - focal adhesion GO:0007165 - signal transduction
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 393
+	Hs
		734903 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		MP2K2_HUMAN (1-391): 2.96e-123: 363: 79.40
+	Hs
		625295 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		805373 HNRPK_HUMAN (1-463): 1.31e-129: 385: 100.00		MP2K3_HUMAN (53-380): 1.39e-65: 214: 36.69
+	Dm
		112942 M9NF14_DROME (115-458): 5.28e-26: 113: 17.77		DSOR1_DROME (12-392): 4.19e-114: 340: 61.42
+	Sp
		252328 RNC1_SCHPO (107-461): 1.39e-21: 98.1: 20.06		HOG1_SCHPO (67-393): 9.11e-120: 352: 20.91
+	Hs
		625452 PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		625540 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		681965 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		AKT1_HUMAN (39-389): 1.97e-120: 359: 19.44
+	Hs
		625451 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		625547 FUBP1_HUMAN (300-460): 2.19e-09: 61.6: 19.64		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		128029 IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57		CDK2_HUMAN (65-367): 2.85e-123: 359: 24.27
+	Hs
		682197 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		AKT2_HUMAN (20-377): 7.89e-112: 337: 20.71
+	Hs
		1027410 FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29		STK3_HUMAN (50-369): 2.6e-109: 331: 33.23
+	Hs
		127987 IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57		CDK1_HUMAN (65-367): 7.64e-110: 325: 26.45
+	Hs
		805422 PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15		MP2K3_HUMAN (53-380): 1.39e-65: 214: 36.69