Interactor 1: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Interactor 2: MECP2 (P51608)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 38697112
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MBD~MBD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000792 - heterochromatin
GO:0001662 - behavioral fear response
GO:0001666 - response to hypoxia
GO:0001964 - startle response
and 61 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 486
Hs

1 486
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 11Aug2025