HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 491
+	Hs
		909512 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		981974 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		STK3_HUMAN (1-491): 1.83e-172: 496: 100.00
+	Hs
		909502 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		904507 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	Hs
		981967 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		STK4_HUMAN (6-491): 3.63e-151: 441: 75.57
+	At
		965291 14332_ARATH (4-244): 1.39e-141: 398: 61.32		CDPK1_ARATH (6-456): 1.49e-140: 418: 20.59
+	At
		802001 14334_ARATH (4-244): 5e-140: 395: 60.91		CDPK1_ARATH (6-456): 1.49e-140: 418: 20.59
+	At
		788694 14335_ARATH (3-244): 5.67e-136: 385: 59.02		CDPK1_ARATH (6-456): 1.49e-140: 418: 20.59
+	Hs
		904516 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PAK2_HUMAN (6-302): 2.65e-119: 361: 41.04
+	Hs
		904514 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		PAK1_HUMAN (6-302): 2.26e-118: 359: 41.81
+	Hs
		850630 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		KS6A3_HUMAN (22-297): 8.86e-98: 312: 28.42
+	Hs
		850642 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		KS6A3_HUMAN (22-297): 8.86e-98: 312: 28.42
+	Hs
		131551 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		STK25_HUMAN (9-426): 4.69e-123: 368: 40.28
+	Hs
		904820 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		M4K3_HUMAN (21-278): 5.12e-76: 257: 47.17
+	Hs
		905305 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		M4K5_HUMAN (1-345): 1.89e-74: 252: 39.94
+	Hs
		909881 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		M4K1_HUMAN (17-278): 3.39e-72: 246: 44.98
+	Hs
		909810 1433E_HUMAN (1-244): 2.02e-141: 398: 63.53		MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43
+	Hs
		904851 1433G_HUMAN (1-247): 3.15e-139: 392: 100.00		MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43
+	Hs
		683216 1433B_HUMAN (2-247): 1.91e-109: 317: 75.40		KS6A3_HUMAN (22-297): 8.86e-98: 312: 28.42
+	Hs
		982271 1433F_HUMAN (1-246): 2.5e-135: 382: 86.99		MINK1_HUMAN (5-316): 3.34e-70: 244: 43.43